To design, develop and commercialize high-performance, cost-effective and sustainable technology solutions across all industries that are touched by chemistry.
Green chemistry is a revolutionary approach to materials design that builds safety and sustainability into the design process from the very beginning — eliminating hazardous substances before they exist, rather than managing them after the fact.
When hazardous materials are removed from products and processes, all hazard-related costs disappear with them — handling, transportation, disposal, compliance, and liability. It is both more environmentally sound and more economically viable than the alternatives.
In 2007, chemist John Warner and entrepreneur Jim Babcock founded the Warner Babcock Institute with a singular purpose: to take green chemistry out of academia and into industry. Warner had spent years co-developing the field's foundational principles — including the 12 Principles of Green Chemistry — and had built the world's first PhD program in the discipline. Babcock brought the institutional and financial experience to turn that science into a commercial reality.
Together they created a new kind of organization — not a university, not a traditional R&D firm, but an innovation factory where green chemistry was not a constraint or a compliance exercise, but the core methodology. WBI became the model for how sustainable chemistry could be practiced at the highest level of scientific rigor, across every industry touched by chemistry.
Meet the founders →Five proprietary technology platforms — from non-covalent derivatization and metal oxide nanotechnology to non-animal toxicology testing — form the scientific backbone of WBI's innovation work.
WBI's expertise spans six major sectors wherever chemistry intersects with environmental and economic performance — from energy and pharmaceuticals to personal care and retail supply chains.
A portfolio of proprietary inventions spanning water harvesting, anti-cancer compounds, Alzheimer's therapeutics, solar energy, and lithium battery recycling — each backed by patents.
Co-inventor of the 12 Principles of Green Chemistry. 2014 Perkin Medal recipient. Named one of "25 Visionaries Changing the World" by Utne Reader.
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Co-founder of global investment bank Babcock & Brown. Harvard Law magna cum laude. Chairman of Cthulhu Ventures, strategic backer of WBI since its founding.
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Former Head of R&D and VP of Marketing at Lonza. BS Chemistry from Yale, PhD Organic Chemistry from Princeton. Appointed CEO of WBI in 2011.
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A scientific discipline dedicated to eliminating hazardous substances at the source — better for the environment, and better for business.
Green Chemistry is a revolutionary approach to the way that products are made — a science that aims to reduce or eliminate the use and generation of hazardous substances during the design phase of materials development. It requires an inventive and interdisciplinary view of material and product design.
Green Chemistry follows the principle that it is better to consider waste prevention options during the design and development phase than to dispose of or treat waste after a process or material has been developed.
Green Chemistry presents industries with incredible opportunity for growth and competitive advantage. We estimate that only 10% of current technologies are environmentally benign; another 25% could be made benign relatively easily. The remaining 65% have yet to be invented.
Green Chemistry also creates cost savings: when hazardous materials are removed from materials and processes, all hazard-related costs are also removed — handling, transportation, disposal, compliance, and liability.
Through Green Chemistry, environmentally benign alternatives to current materials and technologies can be systematically introduced across all types of manufacturing, promoting a more environmentally and economically sustainable future.
In 1990, Congress passed the Pollution Prevention Act, establishing that pollution should be prevented or reduced at the source. In 1991, the EPA adopted this principle as a declared objective. These events provided the groundwork for what would become Green Chemistry.
Several early advocates were instrumental in shaping the movement. Kenneth Hancock, Director of the Division of Chemistry at the NSF, championed the role of chemists in both mitigating environmental effects of past inventions and preventing future problems. Joe Breen, co-founder and first Director of the Green Chemistry Institute in 1997, was a pioneer who toured the world promoting Green Chemistry before his death in 1999 — remembered as the "Heart and Soul of Green Chemistry."
Green Chemistry gained its standing as a scientific discipline through collaboration between government, industry, and academia. In the early 1990s, Paul Anastas — then Chief of the Industrial Chemistry Branch at the EPA — advanced the concept. Working with John Warner, Anastas developed the 12 Principles of Green Chemistry by the mid-1990s.
In 1996, Warner, Anastas, and others were stakeholders in the founding of the Presidential Green Chemistry Challenge Award. In 1998, they published the seminal book Green Chemistry: Theory and Practice, which gave precise definition to the field and enumerated the Twelve Principles. The book has been reprinted in several languages.
In 2007, John Warner returned to industry to develop green technologies, partnering with Jim Babcock to found the Warner Babcock Institute for Green Chemistry — the first company completely dedicated to developing green chemistry technologies.
Countries worldwide have engaged with Green Chemistry as a sustainable development strategy. The year 2000 marked the founding of the Green Chemistry Institute of Spain, the Green and Sustainable Chemistry Network in Japan, and the Centre of Green Chemistry at Monash University in Australia. California became the first state to pass comprehensive Green Chemistry legislation in 2008.
Academic institutions — from the University of Massachusetts and Carnegie Mellon to UC Berkeley and the University of York — have established dedicated Green Chemistry departments, and the field continues to grow in importance on both national and international stages.
Developed by John Warner and Paul Anastas in the 1990s, these twelve principles provide a framework for chemists and engineers to design materials, processes, and products that reduce or eliminate the use and generation of hazardous substances.
Prevent waste rather than treat or clean it up after it has been created.
Design syntheses so that the final product contains the maximum proportion of starting materials.
Design syntheses to use and generate substances with little or no toxicity to people or the environment.
Design chemical products to be fully effective yet have little or no toxicity.
Avoid using solvents, separation agents, or other auxiliary chemicals — or use innocuous ones when necessary.
Run chemical reactions at ambient temperature and pressure whenever possible.
Use starting materials and feedstocks that are renewable rather than depleting.
Minimize or avoid unnecessary derivatization, which requires additional reagents and generates waste.
Use catalytic reagents — as selective as possible — in preference to stoichiometric reagents.
Design chemical products to break down into innocuous substances after use so they don't persist in the environment.
Monitor and control processes in real time to prevent the formation of hazardous substances.
Choose substances and their physical forms to minimize the potential for chemical accidents including releases, explosions, and fires.
WBI's research spans six major industry sectors, underpinned by proprietary core technologies and a growing portfolio of inventions.
All materials are ultimately based on molecules. WBI's green chemistry expertise applies across a wide range of industries where chemistry intersects with environmental and economic performance.
Our work in this sector encompasses solar energy, renewable materials, and clean water. We explore novel photon-to-chemical energy mechanisms for generation and storage, develop alternative fuels from renewable feedstocks, and pursue sustainable approaches to water purification and reclamation.
In response to legislation, rising feedstock prices, and sustainability drivers, industries need alternatives to conventional chemicals and materials. We develop both "drop in" renewable replacements and fundamentally new materials for agrochemicals, textiles, packaging, printing, construction, and related industries.
We develop new materials and application mechanisms that avoid VOCs and remove hazardous substances from industrial products including building and construction materials. We have deep expertise in coating, printing, and imaging technologies, as well as photoresist materials and surface cleaning technologies for electronics and semiconductors.
Green Chemistry within pharmaceutical sciences can create both resource and cost savings. We develop new, more efficient synthetic methods for active pharmaceutical ingredients as well as novel delivery technologies to improve bioavailability and efficacy.
We develop fundamentally new materials and application mechanisms that avoid VOCs and potentially harmful substances for hair, skin, and nail products. We also create strategies for resource and cost savings in both the development and manufacturing of cosmetics and personal care products.
We assess the sustainability of materials and processes that create everyday products — tracing component materials through the supply chain from raw origin through production, distribution, and disposal, and evaluating the impact of current and future regulation on marketplace products.
All materials are ultimately based on molecules. WBI believes it is essential to focus on molecular structure and intermolecular interactions to design sustainable technologies, processes, and products. Our proprietary technology platforms enable this at every scale.
We design, synthesize, and characterize small and medium scale multi-molecular solid-state systems. Our expertise in structure-activity relationships of binary and ternary co-crystalline systems allows us to efficiently manipulate bulk physical properties of materials while avoiding high energies and hazardous reagents.
We create technologies that allow for low energy processing of sol-gels and other dispersive states of metal oxides. These semiconductor and photo-active systems can be coated or incorporated into multi-component systems under ambient conditions while maximizing functional product properties.
We have developed fundamental film-forming and surface coating mechanisms that minimize energy utilization and VOCs. Our strong capabilities in microscopy and surface analysis enable us to characterize and develop a wide variety of sustainable coating solutions.
We have deep expertise in the design, synthesis, and characterization of complex molecules using state-of-the-art tools. Our specialized expertise in functional polymeric materials — creating co-polymeric systems with built-in intermolecular interactions — allows us to control stability and reactivity while providing unique properties.
We develop toxicology screening technologies and chemical sensors that avoid hazardous materials and animal testing. Our in-house capabilities for evaluating new and existing chemicals for human and ecological toxicity include bacteriological testing, cell-based assays, human tissue models, and computational modeling.
WBI has developed a portfolio of proprietary inventions across a range of chemistry domains — from materials science to therapeutics to environmental technology.
WBI has developed materials that extract water from the vapor phase and release it for collection. We have designed proprietary polymers that respond to different wavelengths of light — becoming more hydrophilic in the presence of light, and less hydrophilic in its absence — enabling applications in desalination and air-water harvesting operating under daily solar cycles to rapid millisecond pulses.
WBI has designed several classes of molecules that trigger their surfactancy on or off, enabling water-insoluble components to be mobilized in aqueous systems. Applications include solventless natural products extraction, solventless surface coatings, aqueous encapsulation and delivery technologies, and laundry.
WBI has invented a family of molecules whose molecular and aggregate solubilities can be controlled by irradiation of UV and visible light, enabling positive and negative osmotic pressures across semipermeable membranes. Primary applications are water purification and energy generation and storage. Part of this work was funded by the US Department of Energy.
Traditional processing of photocatalytic TiO₂ semiconductor materials requires sintering at temperatures above 450°C. WBI has developed a technology that creates similar films and structures at room temperature, enabling the use of a wider variety of inexpensive and bio-based substrates alongside significant energy cost savings.
WBI has developed a proprietary family of small molecules showing promise as selective cytostatic anti-cancer agents. NIH NCI cancer screening demonstrated that one compound (RL-4.0) inhibited growth in 55 of 60 cancer cell lines at single-point dosage, with notable activity against colon cancer, melanoma, and prostate cancer.
US 20150065510 PCT WO 2015034785WBI has developed a proprietary family of small molecules showing promise as an Alzheimer's Disease therapy. Nearly 100 derivatives have been synthesized and evaluated, with molecular structure optimized to provide effective EC50 dosages at nanomolar concentrations. Preliminary cognition studies in mice showed improved performance and correlated protein disaggregation of Aβ 1-42 and Aβ 1-40.
US 20140094487 PCT WO 2014052906WBI has developed a proprietary family of small molecules for disaggregation of misfolded proteins — the aggregation of which is mechanistically associated with Alzheimer's, Parkinson's, type 2 diabetes, cystic fibrosis, and cataracts. Early results show effective dosages at nanomolar concentrations.
WBI has created an aqueous flotation system to recover lithium cobalt from e-waste batteries, reproduced at laboratory scale with high efficiency and reproducibility.
US 20140306162 PCT WO 2012177620 EP 2724413A sampling of patents filed and issued through the Warner Babcock Institute and its founders, spanning materials science, photochemistry, solar energy, hair chemistry, battery recycling, pharmaceutical compounds, and more.
Founded in 2007, the Warner Babcock Institute brings together scientific leadership and entrepreneurial vision to advance green chemistry.
WBI was founded in 2007 with a clear mission: to design, develop, and commercialize high-performance, cost-effective, and sustainable technology solutions across all industries touched by chemistry.
Jim Babcock founded what is now Cthulhu Ventures in 2007, and during the same year collaborated with John Warner to found the Warner Babcock Institute for Green Chemistry. Prior to this, he was a co-founder (in 1977), CEO, and ultimately Chairman of Babcock & Brown Limited, a global investment-banking and funds-management firm listed on the Australian Stock Exchange (ASX) in 2004.
Before founding Babcock & Brown, Jim practiced corporate and tax law, having graduated magna cum laude from Harvard College and Harvard Law School, where he was a member and officer of the Harvard Law Review. He served as a law clerk to Judge James R. Browning on the Ninth Circuit Court of Appeals.
Jim serves on the boards of several Cthulhu Ventures companies, including the Warner Babcock Institute for Green Chemistry, Collaborative Medicinal Development, Collaborative Aggregates, and Advantage for Analysts.
John Warner received his BS in Chemistry from UMass Boston and his PhD in Chemistry from Princeton University. After nearly a decade at the Polaroid Corporation, he served as a tenured full professor at UMass Boston and Lowell in Chemistry and Plastics Engineering.
While at Polaroid, Warner co-authored the defining text for the field of Green Chemistry with Paul Anastas and codified the 12 Principles of Green Chemistry. He is editor of the journal Green Chemistry Letters and Reviews, and has served as sustainability advisor for several multinational companies. His research in synthetic organic chemistry, noncovalent derivatization, polymer photochemistry, and low-temperature metal oxide semiconductors underpins his theories of "entropic control in materials design."
John has received awards across academia (PAESMEM, 2004), industry (Perkin Medal, 2014 — the most prestigious award in applied chemistry), and invention (Lemelson Ambassadorship). In 2011 he was elected a Fellow of the American Chemical Society and named one of "25 Visionaries Changing the World" by Utne Reader. He serves as Distinguished Professor of Green Chemistry at Monash University in Australia.
Joe Pont was appointed Chief Executive Officer of the Warner Babcock Institute for Green Chemistry on June 1, 2011. Prior to his appointment, Joe served in senior R&D and commercial roles in the chemical and pharmaceutical industries in the US and Europe, including ten years with Lonza — where he served as Head of Research & Development (2008–2009) and Vice President of Marketing & Key Account Management (2010–2011).
He has extensive experience leading diverse, global organizations and a substantial track record in sales and marketing. Joe holds a BS in Chemistry from Yale University and a PhD in Organic Chemistry from Princeton University.
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Warner Babcock Institute for Green Chemistry, LLC
A subsidiary of Cthulhu Ventures